Calcium Antagonists for Ischemic Stroke
نویسندگان
چکیده
46. Davalos Errando A, De Cendra E, Genis D, Teruel J, Ruibal A, Musoles S. Double-blind controlled trial of nicardipine versus placebo in the treatment of the acute phase of cerebral infarction. Neurologia. 1992;
منابع مشابه
Calcium antagonists for ischemic stroke: a systematic review.
BACKGROUND AND PURPOSE Stroke is a common disease, and many trials with calcium antagonists as possible neuroprotective agents have been conducted. The aim of this review is to determine whether calcium antagonists reduce the risk of death or dependency after acute ischemic stroke. METHODS Acute stroke trials were identified with help of the Cochrane Collaboration Stroke Group and personal co...
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OBJECTIVE Blood pressure variation is one of the factors that affects the risk of stroke recurrence and prognosis. This study investigates the effects of calcium channel blockers and beta-blockers on blood pressure variability in severe ischemic stroke patients. PATIENTS AND METHODS The clinical data of 24 patients with ischemic stroke in our intensive care unit were analyzed, and received am...
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BACKGROUND AND PURPOSE Prolonged inhibition of protein synthesis precedes delayed neuronal death in the CA1 sector of the hippocampus after transient cerebral ischemia. Organic calcium antagonists have been recommended for alleviation of ischemic neuronal damage. The present study was undertaken to investigate whether these drugs improve the recovery of protein biosynthesis after interruption o...
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Ca2+ toxicity remains the central focus of ischemic brain injury. The mechanism by which toxic Ca2+ loading of cells occurs in the ischemic brain has become less clear as multiple human trials of glutamate antagonists have failed to show effective neuroprotection in stroke. Acidosis is a common feature of ischemia and is assumed to play a critical role in brain injury; however, the mechanism(s)...
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Introduction: stroke is the most important brain disease. Stroke leads to a reduction in bone density, altered calcium homeostasis, and an increase in hip fractures. Some recent studies show effects of vitamin D on stroke and vice versa. The purpose of this study was to determine of serum vitamin D levels in patients with acute stroke. Methods: In this cross-sectional study, we compared t...
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